Clinical and Detection of Immunological Study of Rubella Viral in Iraq Women
DOI:
https://doi.org/10.59890/ijsas.v3i3.385Keywords:
Rubella Viral Infections, Pregnancy, IgG Antibodies, IgMAbstract
The clinical definition of rubella is a three-day maculopapular rash. The diagnosis of rubella rash can be challenging since it can resemble other acute viral diseases. As a result, a clinical diagnosis of rubella infection should not be made exclusively. You need serology. It is best to use IgM or IgG seroconversion to diagnose a recent rubella infection. Rubella IgM antibodies show up soon after the disease starts. Antibodies to rubella IgM may last for six months following the original infection. When a patient without rubella IgG antibodies experiences seroconversion, it suggests a fresh infection. Ten days after the rash first appears, seroconversion takes place. IgG for rubella without IgM suggests a recent infection. IgM for rubella is a sign of infection. Should the infection have happened during the first 16 weeks of pregnancy, the unborn child might have CRS. Samples were gathered in Karma Maternity and Emergency Hospital Anbar, Al-Anbar Province, Iraq, and Salahdin Health Directorate, Northern Technical University. Thirty women who had experienced a single or repeated miscarriage and who were sent by a doctor to undergo a (rubella) test to ascertain the precise cause of their loss were chosen for this study. After being extracted from the blood samples, the patients' serum was kept at -80°C in a deep freezer. The MINI VIDAS test method was used to measure the levels of rubella virus IgG and IgM antibodies in blood samples.
References
Abbas, A. B., Moharam, R., & Al-Gmashi, L. (2023). Estimation of Rubella virus antibodies among aborted women in Ibb City-Yemen. J Hum Virol Retrovirol, 10(1), 21-23.
Alaoui, H. L., Seffar, M., Kassouati, J., Zouaki, A., & Kabbaj, H. (2023). Rubella seroprevalence among pregnant women in the region of Rabat, Morocco: a cross-sectional study. BMJ open, 13(6), e067842.
Arnold, B. F., Scobie, H. M., Priest, J. W., & Lammie, P. J. (2018). Integrated serologic surveillance of population immunity and disease transmission. Emerging infectious diseases, 24(7), 1188.
Asrat, B., Shimelis, T., Assefa, A. A., & Hussen, S. (2023). Seroprevalence of rubella virus infection among antenatal care clients of Halaba Town public health facilities, southern Ethiopia. Scientific Reports, 13(1), 7220.
Bechini, A., Zanella, B., Bonito, B., Betti, M., Stancanelli, E., Del Riccio, M., ... & Boccalini, S. (2024). Anti-rubella seroprevalence assessment in an adult sample population in Italy. ANNALI DI IGIENE MEDICINA PREVENTIVA E DI COMUNITÀ, 0-0.
Brady, A. M., El-Badry, E., Padron-Regalado, E., Escudero González, N. A., Joo, D. L., Rota, P. A., & Crooke, S. N. (2024). Serosurveillance for Measles and Rubella. Vaccines, 12(7), 816.
Durowade, K. A., Musa, O. I., Adeniyi, M. A., Sanni, T. A., Salaudeen, A. G., Suleiman, S. T., ... & Durowade, K. A. (2024). Rubella Immunity Gap: A Cross-sectional study on Spatial Distribution, Correlates and Predictors among Women of Reproductive Age, Southwest Nigeria.
Ergün, N. E., Sürmen, S., Ertürk, S., Büyükayhan, D., & Sürmen, M. G. (2023). The Potential Role of Hematological and Biochemical Parameters in Pregnant Women with Viral Infection. Experimed, 13(2), 148-155.
Galle, A., Van Parys, A. S., Roelens, K. and Keygnaert, I. 2015. Expectations and satisfaction with antenatal care among pregnant women with a focus on vulnerable groups: a descriptive study in Ghent. BMC women's health., 15(1): 1-12.
Gorun, F., Malita, D., Ciohat, I., Vilibic-Cavlek, T., Feier, H., Tabain, I., ... & Navolan, D. (2021). Prevalence of Rubella antibodies among fertile women in the west of Romania, 18 Years after the implementation of immunization. Vaccines, 9(2), 104.
Hamad, M. H., Qasem, S., Fadhil, A. A., Alawi, A. M., Hameed, N. A. R., Shnishi, A. T., & Mohammed, N. M. (2022). The Level of Rubella Infection in Women with Recurrent Abortion. Journal of Communicable Diseases (E-ISSN: 2581-351X & P-ISSN: 0019-5138), 54(4), 74-78.
Hodgins, K., & Hill, L. (2021). The future of Rubella IgM testing at Canterbury Health Laboratories. New Zealand Journal of Medical Laboratory Science, 75(3).
Lapić, I., Padoan, A., Bozzato, D., & Plebani, M. (2020). Erythrocyte sedimentation rate and C-reactive protein in acute inflammation: meta-analysis of diagnostic accuracy studies. American journal of clinical pathology, 153(1), 14-29.
Lazim, H. H. and Kadhim, H. S. 2018. Review of sero-prevalence of human cytomegalovirus in Iraq. J Microbiol Exp., 6(2): 50-55.
Leung AKC, Hon KL, Leong KF. Rubella (German measles) revisited. Hong Kong Med J. 2019 Apr;25(2):134-141.
Lulandala, L., Mirambo, M. M., Matovelo, D., Gumodoka, B., & Mshana, S. E. (2017). Acute rubella virus infection among women with spontaneous abortion in Mwanza City, Tanzania. Journal of clinical and diagnostic research: JCDR, 11(3), QC25.
Mao, S., & Wu, L. (2024). Coinfection of viruses in children with community-acquired pneumonia. BMC pediatrics, 24(1), 457.
Mohammed, M., Al-SAADI, M., Kreedy, H. O., Al-Jindeel, T. J., & Al-Karawi, A. S. (2023). Causal Relationship Between Rubella Virus Infections and Bad Obstetric History in Pregnant Women. HIV Nursing, 23(2), 005-011.
Mohammed, R. A., & Kokaz, M. T. (2019). Rubella virus seroprevalence and associated factors in pregnant women with and without previous spontaneous abortion. Medical Journal of Babylon, 16(3), 243-247.
Mohsin, I. H. (2021). The seroprevalence of rubella virus in women and its relationship to abortion in diyala governorate. Biochemical & Cellular Archives, 21(2).
Ross, S. A., Novak, Z., Pati, S. and Boppana, S. B. 2011. Overview of the diagnosis of cytomegalovirus infection. Infectious disorders drug targets., 11(5): 466–474.
Salman. Y.G. Serological Cross Reaction among Songle Causative Agents of Women Abortions (Toxoplasma gondii and Cytmegalo Virus AND Rubella Virus) with the Incidence of Hepatitis Virus (B and C). Tikrit Journal of Pharnnceutical Sciences. 2007; 3 (2):102 – 111.
Shanmugasundaram, D., Viswanathan, R., Winter, A. K., Agarwal, A., Roychowdhury, B., Muliyil, D., ... & Murhekar, M. (2024). Rubella immunity among pregnant women and the burden of congenital rubella syndrome (CRS) in India, 2022. Vaccine, 126077.
T.Hobman, and J. Chantler , Rubella virus: Fields virology,,5th ed., 2007, Lippincott Williams&Wilkins,USA,pp. (1069-1100).
Tabatabaei, S. R., Karimi, A., Alebouyeh, M., Zahed, G., Faghihian, E., Jefrideh, Y., ... & Shariatpanahi, G. (2024). Seroprevalence of Measles and Rubella IgG Antibodies in Children and Pregnant Women in Iran. Archives of Pediatric Infectious Diseases, 12(2).
Tamirat, B., Hussen, S., & Shimelis, T. (2017). Rubella virus infection and associated factors among pregnant women attending the antenatal care clinics of public hospitals in Hawassa City, Southern Ethiopia: a cross-sectional study. BMJ open, 7(10), e016824.
Wang, J., Xu, Y., Wang, X., Liu, Y., Zhang, X., Du, J., ... & Wang, Y. (2022). Epidemiological characteristic of rubella by age group during 12 years after the national introduction of rubella vaccine in Hangzhou, China. Human vaccines & immunotherapeutics, 18(5), 2054208.
Wang, X., Han, Y., Li, C., Wang, M., Yang, B., Zhang, X., & Zhao, L. (2023). Seroepidemiology study of rubella virus antibodies among neonates and pregnant women at hospitals in Henan province, China. Journal of Medical Virology, 95(12), e29340.
Waziri, H. S., Giwa, F., Olayinka, A. T., Waziri, N. E., Da'am, C. K., Mohammed, Y., ... & Olowo-Okere, A. (2024). Rubella seroprevalence among unvaccinated school-aged children in Jos, North Central, Nigeria. The Pan African Medical Journal, 49(1).
World Health Organization, WHO. Data from: rubella vaccines: WHO position paper [Dryad Digital Repository]. 2011. Available: https:// www.who.int/publications/i/item/WER8629
Yan, R., He, H., Deng, X., Zhou, Y., Tang, X., Zhu, Y., ... & RIDPHE Group. (2024). A Serological Survey of Measles and Rubella Antibodies among Different Age Groups in Eastern China. Vaccines, 12(8), 842.


